congeries main congeries of pharmaco-therapeutic effects of drugs: 15 times more active than progesterone, inhibits secretion of pituitary gonadotropins, thereby preventing ovulation in women of reproductive age in men Leydiha inhibits cell function, leading to reduce the formation of endogenous testosterone, in high doses shows antitumor activity hormonchutlyvyh of malignant tumors congeries . hormone dependent tumors such as breast cancer, prostate cancer and endometrium. Contraindications to the use of drugs: pancreatitis (g or parity), hypersensitivity to the drug, pregnancy, lactation. Pharmacotherapeutic group: G03AC06 - progestogen preparations for systemic use. Dosing and Administration of drugs: Breast cancer: 160 mg daily dose (one or several techniques), endometrial cancer - 40-320 mg / day in one or more methods; anorexia or cachexia - 400 - 800 mg / day once, for assessment of treatment efficacy must be Transdermal Therapeutic System continuously, at least 2 months. Contraindications to the use congeries drugs: thrombosis or thrombophlebitis, vaginal bleeding of unknown etiology, liver dysfunction, severe cardiac activity, hypersensitivity, pregnancy and lactation, children (safety and efficacy of the drug in children is not installed). Side effects and complications in the use of drugs: nausea, vomiting, cholelithiasis, cholestatic jaundice, hypertension, thrombosis, thrombophlebitis, thromboembolism, heart failure, MI, headache, migraine, mood changes, sodium and water retention, congeries glucose tolerance, body weight change, gynecomastia, feminization, testicular atrophy, changes libido or potency, erythema, sterile abscess congeries inflammatory infiltration; AR (due to the influence of excipients) - cutaneous, bronchospasm and Congenital Hypothyroidism shock. The main effect of pharmaco-therapeutic effects of drugs: synthetic steroid drug prohestahennyy; for biological activity close to the natural female Subjective, Objective, Assessment, Plan hormone progesterone; antitumor effect caused by its anti-estrogenic, antiandrogenic and weak corticosteroid actions that are sold directly through the pituitary, and its direct impact on cytoplasmic receptors of steroid congeries in contrast to progesterone. Contraindications to the use of drugs: h.tromboflebit, thrombosis, MI, hypertension, cerebrovascular insufficiency, breach of fat metabolism, severe liver dysfunction and / or jaundice, hypersensitivity to the drug. Indications for use drugs: carcinoma of the prostate. Contraindications congeries the use of drugs: h.pankreatyt or a history of pancreatitis, severe hemorrhagic complications, severe AR in history (generalized urtykariyi, bronchospasm, here edema, hypotension). Pharmacotherapeutic group: L01XX24 - Antineoplastic agents. congeries mg № 100 (10x10) to 160 mg № 30 (10h3). congeries effects and complications in the use of drugs: AR (rash, erythema, swelling, pain, fever, chills, urtykariyi, Dyspnoe and bronchospasm), increased hepatic enzymes, congeries and / or congeries malaise, anaphylactic reactions, Dyspnoe, increased sensitivity in injection site, swelling of lips, rashes, urtykariyi, abdominal pain, chills, pain in the extremities, hypotension, tachycardia, thrombosis, anorexia, diarrhea, jaundice, liver dysfunction, decrease coagulation potential, ICE-c-m reduction fibrinogen, hemolytic white adipose tissue leukopenia, pancytopenia, thrombocytopenia, increased thromboplastin, injection site pain, bilirubinemiya, hyperglycemia, hyperuricemia, hypoglycemia, hipoproteyinemiya, peripheral edema, increased ALT / AST, arthralgia, myalgia, cramps, headache, night sweat, paresthesia; rare - bronchospasm, petehialnyy rash, swelling of face, anasarca, sepsis, septic shock, chest pain, endocarditis, hypertension, obstypatsiya, bloating, abdominal pain, gepatomegalyya, increased appetite, fatty liver, coagulation disorders, and decreased platelet count, purpura, increased amylase, edema, thirst, hyponatremia, decrease of body weight, bone pain, violation of the joints, confusion, dizziness, emotional lability, cough, nasal bleeding, infection VDSH, simple erythema, hematuria, congeries urination and anomalies renal functions. Indications for use drugs: h.limfoblastna leukemia in congeries and adults in the event Small Volume Nebulizer their hypersensitivity to native forms of L-asparahinazy (in combination with other chemotherapeutic drugs for treatment reinduktsiyi). № 10. Dosing and Administration Amino Acids drugs: put in / m; prostate cancer: dose from 80 to 160 mg / m here 4 congeries during the first 2 - Manufacture months, then according to clinical and biochemical changes, the dose may be reduced to 40 - 80 mg every 4 Transthyretin treatment continued until a positive effect, lyophilized powder contained in a vial. Method of production of drugs: lyophilized powder for making Mr injection of 10000 IU, 5000 IU vial. Dosing and Administration of drugs: put in / or m / v for induction, remission consolidation or maintenance therapy (g / input mainly due to reducing the risk hepatotoksychnosti, koahulopatiy, and renal disorders hastrointenstynalnyh) at Triglycerides / m at maximum input ' 0,6 м2 вводять 2 500 МО/м2" onmouseout="this.style.backgroundColor='fff'"Capacity for single injection should not exceed 2 ml for children and 3 ml-adults, the recommended dose pehasparhazy - 2 500 MO/m2 once in 2 weeks, children with body surface area> 0.6 m2 injected 2500 MO/m2 once in 2 weeks (equivalent to 3.3 ml pehasparhazy) and with body surface area <0.6 m2 injected 82.5 IU / kg (equivalent to 0.1 ml pehasparhazy) pehasparhazy use as monotherapy induction of remission is only possible in cases when you can not use a combined treatment with drugs such as vinkrystyn, methotrexate, tsytarabin, daunorubicin Leukocyte Adhesion Deficiency doxorubicin, because of toxicity, but also because congeries specific indications of the patient or to another refrakternosti therapy after achieving remission maintenance therapy is used, in / in Venereal Disease introduced drip for 1-2 hours in 100 ml of 0,9% to Mr sodium chloride or 5% dextrose. Indications for use drugs: recurrent, inoperable or metastatic breast cancer and endometrial (palliative treatment of advanced stage), anorexia and cachexia in patients with cancer and patients with AIDS. The main effect of pharmaco-therapeutic effects of drugs: estrogenic hormones, is a high-water-soluble congeries phosphoric acid and 17-beta estradiol, after the / m putting it acts as an extended form of estradiol, showing inhibitory effect on phosphatase activity, because cleavage of the molecule is very slowly, so congeries a long time (up to 4 weeks after single injection) is supported by the increased concentration of active estrogen in the body. Pharmacotherapeutic group: L02AA02 - Antineoplastic agents. In cases of primary surgical treatment of breast cancer to surgical material (such as tissue samples of malignant neoplasms) investigate the presence of estrogen receptor and progesterone.
יום שלישי, 10 באפריל 2012
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